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A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor positive breast cancer

PURPOSE: To compare clinical, immunohistochemical and gene expression models of prognosis applicable to formalin-fixed, paraffin-embedded blocks in a large series of estrogen receptor positive breast cancers, from patients uniformly treated with adjuvant tamoxifen. METHODS: qRT-PCR assays for 50 gen...

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Autori principali: Nielsen, Torsten O., Parker, Joel S, Leung, Samuel, Voduc, David, Ebbert, Mark, Vickery, Tammi, Davies, Sherri R., Snider, Jacqueline, Stijleman, Inge J., Reed, Jerry, Cheang, Maggie C.U., Mardis, Elaine R., Perou, Charles M., Bernard, Philip S., Ellis, Matthew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970720/
https://ncbi.nlm.nih.gov/pubmed/20837693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1282
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