Ionizing radiation activates the Nrf2 antioxidant response

The transcription factor Nrf2 binds the antioxidant DNA response element (ARE) to activate important cellular cytoprotective defense systems. Recently several types of cancers have been shown to overexpress Nrf2, but its role in the cellular response to radiation therapy has yet to be fully determin...

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Main Authors: McDonald, J. Tyson, Kim, Kwanghee, Norris, Andrew, Vlashi, Erina, Phillips, Tiffany M., Lagadec, Chann, Donna, Lorenza Della, Ratikan, Josephine, Szelag, Heather, Hlatky, Lynn, McBride, William H.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970706/
https://ncbi.nlm.nih.gov/pubmed/20940400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0171
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