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Ionizing radiation activates the Nrf2 antioxidant response

The transcription factor Nrf2 binds the antioxidant DNA response element (ARE) to activate important cellular cytoprotective defense systems. Recently several types of cancers have been shown to overexpress Nrf2, but its role in the cellular response to radiation therapy has yet to be fully determin...

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Detalhes bibliográficos
Main Authors: McDonald, J. Tyson, Kim, Kwanghee, Norris, Andrew, Vlashi, Erina, Phillips, Tiffany M., Lagadec, Chann, Donna, Lorenza Della, Ratikan, Josephine, Szelag, Heather, Hlatky, Lynn, McBride, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970706/
https://ncbi.nlm.nih.gov/pubmed/20940400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0171
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