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Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics

BACKGROUND: Cancer stem cells are presumed to have virtually unlimited proliferative and self-renewal abilities and to be highly resistant to chemotherapy, a feature that is associated with overexpression of ATP-binding cassette transporters. We investigated whether prolonged continuous selection of...

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Detalhes bibliográficos
Main Authors: Calcagno, Anna Maria, Salcido, Crystal D., Gillet, Jean-Pierre, Wu, Chung-Pu, Fostel, Jennifer M., Mumau, Melanie D., Gottesman, Michael M., Varticovski, Lyuba, Ambudkar, Suresh V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970576/
https://ncbi.nlm.nih.gov/pubmed/20935265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq361
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