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Vκ polymorphisms in NOD mice are spread throughout the entire immunoglobulin kappa locus and are shared by other autoimmune strains

The diversity of immunoglobulin (Ig) and T cell receptor (TCR) genes available to form the lymphocyte repertoire has the capacity to produce a broad array of both protective and harmful specificities. In type 1 diabetes (T1D), the presence of antibodies to insulin and other islet antigens predicts d...

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Detalhes bibliográficos
Main Authors: Henry, Rachel A., Kendall, Peggy L., Woodward, Emily J., Hulbert, Chrys, Thomas, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970566/
https://ncbi.nlm.nih.gov/pubmed/20556377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-010-0457-9
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