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Violations of the 12/23 rule at the mouse immunoglobulin kappa locus, including Vκ-Vκ rearrangement
Classically, recombination between immunoglobulin gene segments uses a pair of recombination signal sequences (RSSs) with dissimilar spacers (the “12/23 rule”). Using a series of different genotyping assays, four different kinds of atypical rearrangements were identified at the murine kappa locus: (...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697664/ https://ncbi.nlm.nih.gov/pubmed/19467709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.04.021 |
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