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Violations of the 12/23 rule at the mouse immunoglobulin kappa locus, including Vκ-Vκ rearrangement

Classically, recombination between immunoglobulin gene segments uses a pair of recombination signal sequences (RSSs) with dissimilar spacers (the “12/23 rule”). Using a series of different genotyping assays, four different kinds of atypical rearrangements were identified at the murine kappa locus: (...

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Detalhes bibliográficos
Main Authors: Vinocur, Jeffrey M., Fesnak, Andrew D., Liu, Yang, Charan, Deepshikha, Luning Prak, Eline T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697664/
https://ncbi.nlm.nih.gov/pubmed/19467709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.04.021
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