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p21-Activated Kinases Are Required for Transformation in a Cell-Based Model of Neurofibromatosis Type 2
BACKGROUND: NF2 is an autosomal dominant disease characterized by development of bilateral vestibular schwannomas and other benign tumors in central nervous system. Loss of the NF2 gene product, Merlin, leads to aberrant Schwann cell proliferation, motility, and survival, but the mechanisms by which...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970553/ https://ncbi.nlm.nih.gov/pubmed/21072183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013791 |
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