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The Inhibitory Effect of Heme on Heme Formation In Vivo: Possible Mechanism for the Regulation of Hemoglobin Synthesis

1) The effect of hemin on heme synthesis was studied in vivo. Heme synthesis was measured by determining red cell (59)Fe uptake and glycine-2-(14)C incorporation into red cell hemin in normal CF(1) female mice. 2) Both bovine and human hemin significantly decreased red cell (59)Fe uptake 48, 72, and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awdur: Gallo, Robert C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 1967
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297027/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6019399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105505
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