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The Inhibitory Effect of Heme on Heme Formation In Vivo: Possible Mechanism for the Regulation of Hemoglobin Synthesis

1) The effect of hemin on heme synthesis was studied in vivo. Heme synthesis was measured by determining red cell (59)Fe uptake and glycine-2-(14)C incorporation into red cell hemin in normal CF(1) female mice. 2) Both bovine and human hemin significantly decreased red cell (59)Fe uptake 48, 72, and...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Autor principal: Gallo, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1967
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297027/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6019399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105505
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