The proximal element of the beta globin locus control region is not functionally required in vivo.

In addition to local sequence elements the regulation of the high-level, development- and tissue-specific expression of the human beta globin gene cluster appears to require distant regulatory sequences which have been termed locus control region. In the chromatin of erythroid cells the locus contro...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Kulozik, A E, Bail, S, Bellan-Koch, A, Bartram, C R, Kohne, E, Kleihauer, E
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296972/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2040696/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115246
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