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The proximal element of the beta globin locus control region is not functionally required in vivo.

In addition to local sequence elements the regulation of the high-level, development- and tissue-specific expression of the human beta globin gene cluster appears to require distant regulatory sequences which have been termed locus control region. In the chromatin of erythroid cells the locus contro...

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Hlavní autoři: Kulozik, A E, Bail, S, Bellan-Koch, A, Bartram, C R, Kohne, E, Kleihauer, E
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC296972/
https://ncbi.nlm.nih.gov/pubmed/2040696
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