Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer

Checkpoint kinase 2 (CHEK2) is a protein involved in arresting cell cycle in response to DNA damage. To investigate whether it plays an important role in the development of prostate cancer (PRCA) in the Ashkenazi Jewish (AJ) population, we sequenced CHEK2 in 75 AJ individuals with prostate, breast,...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Tischkowitz, Marc D., Yilmaz, Ahmet, Chen, Long Q., Karyadi, Danielle M., Novak, David, Kirchhoff, Tomas, Hamel, Nancy, Tavtigian, Sean V., Kolb, Suzanne, Bismar, Tarek A., Aloyz, Raquel, Nelson, Peter S., Hood, Lee, Narod, Steven A., White, Kirsten A., Ostrander, Elaine A., Isaacs, William B., Offit, Kenneth, Cooney, Kathleen A., Stanford, Janet L., Foulkes, William D.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2008
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2969172/
https://ncbi.nlm.nih.gov/pubmed/18571837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.05.006
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