Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer

Checkpoint kinase 2 (CHEK2) is a protein involved in arresting cell cycle in response to DNA damage. To investigate whether it plays an important role in the development of prostate cancer (PRCA) in the Ashkenazi Jewish (AJ) population, we sequenced CHEK2 in 75 AJ individuals with prostate, breast,...

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Detalhes bibliográficos
Main Authors: Tischkowitz, Marc D., Yilmaz, Ahmet, Chen, Long Q., Karyadi, Danielle M., Novak, David, Kirchhoff, Tomas, Hamel, Nancy, Tavtigian, Sean V., Kolb, Suzanne, Bismar, Tarek A., Aloyz, Raquel, Nelson, Peter S., Hood, Lee, Narod, Steven A., White, Kirsten A., Ostrander, Elaine A., Isaacs, William B., Offit, Kenneth, Cooney, Kathleen A., Stanford, Janet L., Foulkes, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2969172/
https://ncbi.nlm.nih.gov/pubmed/18571837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.05.006
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