Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma.

Interferon-gamma (IFN-gamma) is a lymphokine that activates mononuclear phagocytes. To test the hypothesis that IFN-gamma might have important effects upon the ability of human mononuclear phagocytes to degrade extracellular matrix, we have studied the action of this cytokine on the production of me...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Shapiro, S D, Campbell, E J, Kobayashi, D K, Welgus, H G
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1990
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296850/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2170447/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114826
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