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Molecular basis of hereditary C3 deficiency.

Hereditary deficiency of complement component C3 in a 10-yr-old boy was studied. C3 could not be detected by RIA of serum from the patient. Segregation of C3 S and C3 F allotypes within the family confirmed the presence of a null gene for C3, for which the patient was homozygous. 30 exons have been...

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Detalhes bibliográficos
Main Authors: Botto, M, Fong, K Y, So, A K, Rudge, A, Walport, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296845/
https://ncbi.nlm.nih.gov/pubmed/2212005
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