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Two distinct abnormalities in patients with C8 alpha-gamma deficiency. Low level of C8 beta chain and presence of dysfunctional C8 alpha-gamma subunit.

The sera from three C8 alpha-gamma deficient patients previously reported to have a selective C8 alpha-gamma defect were analyzed by SDS-PAGE and Western blot using two polyclonal antisera to C8 alpha-gamma and a monoclonal antibody to C8 alpha. All three sera exhibited C8 alpha-gamma bands that dis...

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Publikašuvnnas:J Clin Invest
Váldodahkkit: Tedesco, F, Roncelli, L, Petersen, B H, Agnello, V, Sodetz, J M
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Clinical Investigation 1990
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296807/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2394837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114789
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