Interleukin 1 inhibits insulin secretion from isolated rat pancreatic islets by a process that requires gene transcription and mRNA translation.

Recombinant human IL 1 beta inhibits glucose-induced insulin secretion from isolated pancreatic islets and from purified beta-cells obtained by fluorescence-activated cell sorting (FACS) of dispersed islet cells. Brief (1 h) exposure of isolated islets to IL 1 produces sustained inhibition of insuli...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Hughes, J H, Colca, J R, Easom, R A, Turk, J, McDaniel, M L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2203826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114785
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