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Selective substitution of amino acids limits proteolytic cleavage and improves the bioactivity of an anti-biofilm peptide that targets the periodontal pathogen, Porphyromonas gingivalis

The interaction of the periodontal pathogen, Porphyromonas gingivalis with oral streptococci such as Streptococcus gordonii precedes colonization of the subgingival pocket and represents a target for limiting P. gingivalis colonization of the oral cavity. Previous studies showed that a synthetic pep...

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Bibliografiske detaljer
Main Authors: Daep, Carlo Amorin, Novak, Elizabeth A., Lamont, Richard J., Demuth, Donald R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967622/
https://ncbi.nlm.nih.gov/pubmed/20800634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.08.014
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