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Selective substitution of amino acids limits proteolytic cleavage and improves the bioactivity of an anti-biofilm peptide that targets the periodontal pathogen, Porphyromonas gingivalis
The interaction of the periodontal pathogen, Porphyromonas gingivalis with oral streptococci such as Streptococcus gordonii precedes colonization of the subgingival pocket and represents a target for limiting P. gingivalis colonization of the oral cavity. Previous studies showed that a synthetic pep...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967622/ https://ncbi.nlm.nih.gov/pubmed/20800634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.08.014 |
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