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Educating CD4 T cells with vaccine adjuvants: lessons from lipopolysaccharide
Toll-like receptor (TLR) adjuvants are capable of driving T cell immunity. The TLR4 agonist LPS activates antigen-presenting cells through MyD88- and TRIF-dependent signaling pathways, which initiates CD4 T helper cell clonal expansion and differentiation. Lipopolysaccharide (LPS) supports the devel...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967613/ https://ncbi.nlm.nih.gov/pubmed/20880743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2010.08.005 |
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