Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization

Lipopolysaccharide (LPS) is a potent natural adjuvant, commonly used to amplify Th1 responses. Here, we report that systemic immunization using LPS generates large numbers of specific Th17 cells in murine small intestinal lamina propria. The priming of these Th17 cells required IL-23p19 production b...

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Detaylı Bibliyografya
Asıl Yazarlar: McAleer, Jeremy P., Liu, Bei, Li, Zihai, Ngoi, Soo-Mun, Dai, Jie, Oft, Martin, Vella, Anthony T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Society for Leukocyte Biology 2010
Konular:
Spotlight on Leading Edge Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892526/
https://ncbi.nlm.nih.gov/pubmed/20130220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0909631
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