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Preferential antitumor effect of the Src inhibitor dasatinib associated with a decreased proportion of aldehyde dehydrogenase 1-positive cells in breast cancer cells of the basal B subtype

BACKGROUND: Recent studies have suggested that the Src inhibitor dasatinib preferentially inhibits the growth of breast cancer cells of the basal-like subtype. To clarify this finding and further investigate combined antitumor effects of dasatinib with cytotoxic agents, a panel of breast cancer cell...

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Detalhes bibliográficos
Main Authors: Kurebayashi, Junichi, Kanomata, Naoki, Moriya, Takuya, Kozuka, Yuji, Watanabe, Mika, Sonoo, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967550/
https://ncbi.nlm.nih.gov/pubmed/20959018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-568
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