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Paradoxical expression of adenosine deaminase in T cells cultured from a patient with adenosine deaminase deficiency and combine immunodeficiency.

T lymphocytes cultured from a patient (T.D.) with adenosine deaminase (ADA) deficiency expressed ADA activity in the normal range, inconsistent with her severe immunodeficiency, metabolic abnormalities, and with the absence of ADA activity in her B lymphocytes and other nucleated hematopoietic cells...

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Pubblicato in:J Clin Invest
Autori principali: Arredondo-Vega, F X, Kurtzberg, J, Chaffee, S, Santisteban, I, Reisner, E, Povey, M S, Hershfield, M S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1974554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114730
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