Variability in Timing of Spontaneous Calcium Release in the Intact Rat Heart is Determined by the Time Course of Sarcoplasmic Reticulum Calcium Load

BACKGROUND: Abnormalities in intracellular calcium (Ca) cycling during Ca overload can cause triggered activity because spontaneous calcium release (SCR) activates sufficient Ca-sensitive inward currents to induce delayed afterdepolarizations (DADs). However, little is known about the mechanisms rel...

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Detalhes bibliográficos
Main Authors: Wasserstrom, J. Andrew, Shiferaw, Yohannes, Chen, Wei, Ramakrishna, Satvik, Patel, Heetabh, Kelly, James E., O’Toole, Matthew J., Pappas, Amanda, Chirayil, Nimi, Bassi, Nikhil, Akintilo, Lisa, Wu, Megan, Arora, Rishi, Aistrup, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967435/
https://ncbi.nlm.nih.gov/pubmed/20829511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.229294
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