Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors.

Propagation of venous thrombi or rethrombosis after coronary thrombolytic therapy can occur despite heparin administration. To explore potential mechanisms, we set out to determine whether clot-bound thrombin is relatively protected from inhibition by heparin-antithrombin III but susceptible to inac...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Weitz, J I, Hudoba, M, Massel, D, Maraganore, J, Hirsh, J
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1990
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2384594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114723
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