Urokinase has direct catalytic activity against fibrinogen and renders it less clottable by thrombin.
Recently, we demonstrated that tissue plasminogen activator directly releases fibrinopeptides A and B (FPA and FPB) from fibrinogen. The purpose of this study was to determine whether urokinase has similar activity. Incubation of urokinase with fibrinogen or heparinized plasma results in concentrati...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1990
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2365816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114685 |
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