Urokinase has direct catalytic activity against fibrinogen and renders it less clottable by thrombin.

Recently, we demonstrated that tissue plasminogen activator directly releases fibrinopeptides A and B (FPA and FPB) from fibrinogen. The purpose of this study was to determine whether urokinase has similar activity. Incubation of urokinase with fibrinogen or heparinized plasma results in concentrati...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Weitz, J I, Leslie, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2365816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114685
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