Adjuvant chemoradiotherapy of advanced resectable rectal cancer: results of a randomised trial comparing modulation of 5-fluorouracil with folinic acid or with interferon-α

BACKGROUND: Standard adjuvant chemoradiotherapy of rectal cancer still consists of 5-fluorouracil (5-FU) only. Its cytotoxicity is enhanced by folinic acid (FA) and interferon-α (INFα). In this trial, the effects of FA and IFNα on adjuvant 5-FU chemoradiotherapy in locally advanced rectal cancer wer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kornmann, M, Staib, L, Wiegel, T, Kreuser, E-D, Kron, M, Baumann, W, Henne-Bruns, D, Link, K-H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Clinical Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967051/
https://ncbi.nlm.nih.gov/pubmed/20877353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605871
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