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Increase of Survival Benefit in Advanced Resectable Colon Cancer by Extent of Adjuvant Treatment: Results of a Randomized Trial Comparing Modulation of 5-FU + Levamisole With Folinic Acid or With Interferon-α

BACKGROUND: The benefit of adjuvant therapy in curatively resected lymph node-positive colon cancer was established using 5-fluorouracil (5-FU) and levamisole (LEV) for 12 months. 5-FU cytotoxicity can be modulated by folinic acid (FA) or interferon-α (INF-α). The aim of this study was to investigat...

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Detalhes bibliográficos
Main Authors: Link, Karl-Heinz, Kornmann, Marko, Staib, Ludger, Redenbacher, Martin, Kron, Martina, Beger, Hans Günter
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1357722/
https://ncbi.nlm.nih.gov/pubmed/16041207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000171033.65639.a9
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