Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance.

The present studies investigated the expression of the two PDGF genes (c-sis/PDGF-2 and PDGF-1) and the PDGF-receptor b gene (PDGF-R) in 34 primary human astrocytomas. Northern blot analysis demonstrated the coexpression of the c-sis/PDGF-2 protooncogene and the PDGF-R gene in all astrocytomas exami...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Maxwell, M, Naber, S P, Wolfe, H J, Galanopoulos, T, Hedley-Whyte, E T, Black, P M, Antoniades, H N
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1990
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296700/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164040/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114675
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