Protein phosphatase 1γ is responsible for dephosphorylation of histone H3 at Thr 11 after DNA damage

The DNA-damage-induced transcriptional suppression of cell cycle regulatory genes correlates with a reduction in histone H3-Thr 11 phosphorylation (H3-pThr 11) on their promoters that is partly mediated by the dissociation of Chk1 from chromatin. In this study, we identify protein phosphatase 1γ (PP...

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Main Authors: Shimada, Midori, Haruta, Mayumi, Niida, Hiroyuki, Sawamoto, Kazunobu, Nakanishi, Makoto
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Scientific Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966955/
https://ncbi.nlm.nih.gov/pubmed/20948546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.152
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