The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response

The function of protein phosphatase 1 nuclear-targeting subunit (PNUTS)—one of the most abundant nuclear-targeting subunits of protein phosphatase 1 (PP1c)—remains largely uncharacterized. We show that PNUTS depletion by small interfering RNA activates a G2 checkpoint in unperturbed cells and prolon...

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Detalhes bibliográficos
Main Authors: Landsverk, Helga B, Mora-Bermúdez, Felipe, Landsverk, Ole J B, Hasvold, Grete, Naderi, Soheil, Bakke, Oddmund, Ellenberg, Jan, Collas, Philippe, Syljuåsen, Randi G, Küntziger, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966950/
https://ncbi.nlm.nih.gov/pubmed/20890310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.134
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