Lycorine sensitizes CD40 ligand-protected chronic lymphocytic leukemia cells to bezafibrate- and medroxyprogesterone acetate-induced apoptosis but dasatanib does not overcome reported CD40-mediated drug resistance

BACKGROUND: Tumor cells in chronic lymphocytic leukemia accumulate in the periphery through the proliferation of a minority of cells in lymph nodes. The proliferative and survival signals in these proliferation centers include interactions with T lymphocytes expressing CD40 ligand. We have demonstra...

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Main Authors: Hayden, Rachel E., Pratt, Guy, Drayson, Mark T., Bunce, Chris M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966911/
https://ncbi.nlm.nih.gov/pubmed/20634492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.027821
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