Combined bezafibrate, medroxyprogesterone acetate and valproic acid treatment inhibits osteosarcoma cell growth without adversely affecting normal mesenchymal stem cells

Drug repurposing is a cost-effective means of targeting new therapies for cancer. We have examined the effects of the repurposed drugs, bezafibrate, medroxyprogesterone acetate and valproic acid on human osteosarcoma cells, i.e., SAOS2 and MG63 compared with their normal cell counterparts, i.e. mese...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Sheard, Jonathan J., Southam, Andrew D., MacKay, Hannah L., Ellington, Max A., Snow, Martyn D., Khanim, Farhat L., Bunce, Christopher M., Johnson, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786328/
https://ncbi.nlm.nih.gov/pubmed/33289496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20202505
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