Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone.

Little is known about endogenous systemic lupus erythematosus (SLE) plasma DNA even though it is the presumed precursor of DNA-containing immune complexes, thought to play a central role in lupus glomerulonephritis. DNA purified from SLE plasma formed discrete bands, corresponding to sizes of about...

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Pubblicato in:	J Clin Invest
Autori principali:	Rumore, P M, Steinman, C R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2365827/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114716
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