Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone.

Little is known about endogenous systemic lupus erythematosus (SLE) plasma DNA even though it is the presumed precursor of DNA-containing immune complexes, thought to play a central role in lupus glomerulonephritis. DNA purified from SLE plasma formed discrete bands, corresponding to sizes of about...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Rumore, P M, Steinman, C R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2365827/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114716
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