Constitutive and B-cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma

BACKGROUND: The deregulation of several transcription factors contribute to the aggressive course of mantle cell lymphoma. This study focuses on survival signals emanating from the tumor environment and involving the signal transducer and activator of transcription (STAT) 3 through cytokines or anti...

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Detalhes bibliográficos
Main Authors: Baran-Marszak, Fanny, Boukhiar, Mohand, Harel, Stéphanie, Laguillier, Christelle, Roger, Claudine, Gressin, Remy, Martin, Antoine, Fagard, Remi, Varin-Blank, Nadine, Ajchenbaum-Cymbalista, Florence, Ledoux, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966908/
https://ncbi.nlm.nih.gov/pubmed/20663948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.019745
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