A Triplex Ribozyme Expression System Based on a Single Hairpin Ribozyme

Triplex ribozyme (RZ) configurations allow for the individual activity of trans-acting RZs in multiple expression cassettes (multiplex), thereby increasing target cleavage relative to conventionally expressed RZs. Although hairpin RZs have been advantageously compared to hammerhead RZs, their longer...

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Autori principali: Aquino-Jarquin, Guillermo, Benítez-Hess, María Luisa, DiPaolo, Joseph A., Alvarez-Salas, Luis M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2008
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966833/
https://ncbi.nlm.nih.gov/pubmed/18707243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2008.0130
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