Characterization of a Mouse Model of Hyperglycemia and Retinal Neovascularization

One of the limitations of research into diabetic retinopathy is the lack of suitable animal models. To study how the two important factors—hyperglycemia and vascular endothelial growth factor—interact in diabetic retinopathy, the Akimba mouse (Ins2(Akita)VEGF(+/−)) was generated by crossing the Akit...

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Autori principali: Rakoczy, Elizabeth P., Rahman, Ireni S. Ali, Binz, Nicolette, Li, Cai-Rui, Vagaja, Nermina N., de Pinho, Marisa, Lai, Chooi-May
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2010
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966820/
https://ncbi.nlm.nih.gov/pubmed/20829433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090883
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