Lack of Fetuin-A (α(2)-HS-Glycoprotein) Reduces Mammary Tumor Incidence and Prolongs Tumor Latency via the Transforming Growth Factor-β Signaling Pathway in a Mouse Model of Breast Cancer

The present analyses were done to define the role of fetuin-A (Fet) in mammary tumorigenesis using the polyoma middle T antigen (PyMT) transgenic mouse model. We crossed Fet-null mice in the C57BL/6 background with PyMT mice in the same background and after a controlled breeding protocol obtained Py...

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Hlavní autoři: Guillory, Bobby, Sakwe, Amos M., Saria, Margret, Thompson, Pamela, Adhiambo, Christine, Koumangoye, Rainelli, Ballard, Billy, Binhazim, Awadh, Cone, Cecil, Jahanen-Dechent, Willi, Ochieng, Josiah
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966818/
https://ncbi.nlm.nih.gov/pubmed/20847285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100177
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