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Mitochondrial DNA Content and Lung Cancer Risk
Smoky coal contains polycyclic aromatic hydrocarbons (PAHs) and has been strongly implicated in etiology of lung cancer in Xuan Wei, China. While PAHs have been demonstrated to form bulky adducts in nuclear DNA, they have a 90-fold greater affinity for mitochondrial DNA (mtDNA). To compensate for mi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966769/ https://ncbi.nlm.nih.gov/pubmed/18691788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2008.06.012 |
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