Ligation of CD11c during vaccination promotes germinal centre induction and robust humoral responses without adjuvant

In this study, we investigated the mouse dendritic cell (DC) receptor, complement receptor 4 (CR4; CD11c/CD18), as an immunotarget for triggering humoral immunity. Comparison of antibody titres generated against a panel of 13 anti-antigen-presenting cell receptor monoclonal antibodies, with or witho...

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Detalhes bibliográficos
Principais autores: White, Ann L, Tutt, Alison L, James, Sonya, Wilkinson, Kevin A, Castro, Fernanda V V, Dixon, Sandra V, Hitchcock, Jessica, Khan, Mahmood, Al-Shamkhani, Aymen, Cunningham, Adam F, Glennie, Martin J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966766/
https://ncbi.nlm.nih.gov/pubmed/20465572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03285.x
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