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CD4(+) T cells against human papillomavirus-18 E7 in patients with high-grade cervical lesions associate with the absence of the virus in the cervix

Cervical neoplastic lesions are associated with infection by high-risk human papilloma-viruses (HPV). The two genotypes most frequently found in the lesions are HPV-16 and HPV-18 with a prevalence of 50–60% and 15–18%, respectively. The E6 and E7 viral oncoproteins are involved in the transformation...

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Detalhes bibliográficos
Main Authors: Seresini, Samantha, Origoni, Massimo, Caputo, Luigi, Lillo, Flavia, Longhi, Renato, Vantini, Simone, Paganoni, Anna Maria, Protti, Maria Pia
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966761/
https://ncbi.nlm.nih.gov/pubmed/20545782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03277.x
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