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Estimating Point and Interval Frequency of Antigen-Specific CD4(+) T Cells Based on Short In Vitro Expansion and Improved Poisson Distribution Analysis
BACKGROUND: Knowledge of antigen-specific CD4(+) T cells frequencies is pivotal to the choice of the antigen to be used in anti-viral and anti-tumor vaccination procedures and for monitoring of immune responses. Methods that employ small cell numbers from patient samples, are easy to perform and do...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413706/ https://ncbi.nlm.nih.gov/pubmed/22879946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042340 |
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