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Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response
T-cell immunoglobulin mucin-1 (Tim-1) has been proposed to be an important T-cell immunoregulatory molecule since its expression on activated T cells was discovered. To study the role of Tim-1 on T cells in vitro and in vivo we generated both Tim-1-deficient mice and several lines of Tim-1 transgeni...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966760/ https://ncbi.nlm.nih.gov/pubmed/20518819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03276.x |
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