Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response

T-cell immunoglobulin mucin-1 (Tim-1) has been proposed to be an important T-cell immunoregulatory molecule since its expression on activated T cells was discovered. To study the role of Tim-1 on T cells in vitro and in vivo we generated both Tim-1-deficient mice and several lines of Tim-1 transgeni...

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Autors principals: Wong, See Heng, Barlow, Jillian L, Nabarro, Stephen, Fallon, Padraic G, McKenzie, Andrew N J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2010
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966760/
https://ncbi.nlm.nih.gov/pubmed/20518819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03276.x
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