Common Variants of TLR1 Associate with Organ Dysfunction and Sustained Pro-Inflammatory Responses during Sepsis

BACKGROUND: Toll-like receptors (TLRs) are critical components for host pathogen recognition and variants in genes participating in this response influence susceptibility to infections. Recently, TLR1 gene polymorphisms have been found correlated with whole blood hyper-inflammatory responses to path...

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Autori principali: Pino-Yanes, Maria, Corrales, Almudena, Casula, Milena, Blanco, Jesús, Muriel, Arturo, Espinosa, Elena, García-Bello, Miguel, Torres, Antoni, Ferrer, Miguel, Zavala, Elizabeth, Villar, Jesús, Flores, Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966434/
https://ncbi.nlm.nih.gov/pubmed/21048935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013759
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