Common Variants of TLR1 Associate with Organ Dysfunction and Sustained Pro-Inflammatory Responses during Sepsis

BACKGROUND: Toll-like receptors (TLRs) are critical components for host pathogen recognition and variants in genes participating in this response influence susceptibility to infections. Recently, TLR1 gene polymorphisms have been found correlated with whole blood hyper-inflammatory responses to path...

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Detalhes bibliográficos
Main Authors: Pino-Yanes, Maria, Corrales, Almudena, Casula, Milena, Blanco, Jesús, Muriel, Arturo, Espinosa, Elena, García-Bello, Miguel, Torres, Antoni, Ferrer, Miguel, Zavala, Elizabeth, Villar, Jesús, Flores, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966434/
https://ncbi.nlm.nih.gov/pubmed/21048935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013759
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