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Target DNA chromatinization modulates nicking by L1 endonuclease

L1 elements are human transposons which replicate via an RNA intermediate. At least 15% of the human genome is composed of L1 sequence. An important initial step in the transposition reaction is nicking of the genomic DNA by L1 endonuclease (L1 EN). In vivo much of the genome exists in the form of c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cost, Gregory J., Golding, Amit, Schlissel, Mark S., Boeke, Jef D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC29664/
https://ncbi.nlm.nih.gov/pubmed/11139628
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