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Regulation of immunoglobulin (Ig)E synthesis in the hyper-IgE syndrome.

The hyper-IgE (HIE) syndrome is characterized by high IgE serum levels, chronic dermatitis, and recurrent infections. The mechanisms responsible for hyperproduction of IgE in HIE patients are presently unknown. We investigated whether spontaneous in vitro IgE synthesis by PBMC from seven HIE patient...

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Udgivet i:J Clin Invest
Principais autores: Vercelli, D, Jabara, H H, Cunningham-Rundles, C, Abrams, J S, Lewis, D B, Meyer, J, Schneider, L C, Leung, D Y, Geha, R S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2110192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114618
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